Partners & Resources
WIRE's research is made possible by institutional partnerships and shared data infrastructure at the Medical College of Wisconsin.
Center for Advancing Population Science (CAPS)
Much of WIRE's biostatistical support — particularly for large target trial emulations and complex observational analyses — is provided by the expert biostatisticians at the Center for Advancing Population Science (CAPS) at MCW. CAPS brings deep expertise in population-level research design, causal inference methods, and advanced statistical modeling, enabling WIRE to pursue methodologically ambitious studies with the analytic rigor they demand.
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CTSI SE Wisconsin — Center for Biomedical Informatics (CRDW)
WIRE leverages multiple Clinical Research Data Warehouse (CRDW) resources to support our research, including TriNetX (individual patient-level data), i2b2, and ENACT. These platforms enable large-scale cohort identification, feasibility assessments, and real-world data analyses that are foundational to our observational and implementation research. All CRDW resources are supported by the Medical College of Wisconsin CTSA Grant UL1TR001436.
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REDCap (through CTSI SE Wisconsin)
REDCap (Research Electronic Data Capture) is WIRE's primary platform for clinical trial data collection and management. Hosted through CTSI SE Wisconsin, REDCap provides secure, HIPAA-compliant electronic case report forms (eCRFs), randomization modules, and data validation tools that support the full lifecycle of our clinical studies — from prospective registries to multicenter randomized trials.
Florence eBinders
Florence eBinders is WIRE's electronic regulatory binder platform for clinical trial document management. Florence provides a centralized, 21 CFR Part 11-compliant system for organizing, storing, and sharing essential regulatory documents — including IRB approvals, informed consent forms, delegation logs, and monitoring visit records — streamlining trial oversight and ensuring audit-readiness across all of our studies.